Journal: PLOS One
Article Title: Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study
doi: 10.1371/journal.pone.0336221
Figure Lengend Snippet: The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
Article Snippet: Monoclonal antibodies were against PGC-1α (ab54481, Abcam), NF-κB p65 (ab16502, Abcam), Drp-1 (sc-271583), ATF3 (sc-518032), p-p53 (sc-377553), p-p21 (sc-377569), and caspase-3 (sc-7272) (Santa Cruz Biotechnology, Inc).
Techniques: Western Blot, Control